Washington University of St. Louis Cell Biology and Physiology in St. Louis, Missouri

Post Doc Instructions

Please do not submit an application to this posting. To apply for this postdoctoral research opportunity, follow the directions below in “Applicant Special Instructions”.

Job Type/Schedule

This position is full-time and works approximately 40 hours per week. Hours are generally normal business hours but may vary due to the timing of experiments and other research activity deadlines.

Department Name/Job Location

This position is in the Department of Cell Biology and Physiology. This position is for the Medical School Campus.

Essential Functions

The actin cytoskeleton is an intricate polymer system that can be assembled into many different structures, ranging from stable stress fibers that locally support cell adhesion, to the extensive and dynamic branched network at the leading edge that drives cell migration. However, a question that keeps intriguing the field is how this plethora of structures, each with their own particular turnover rates and physical properties, can be assembled in the same cytosol from the same basic building blocks, i.e. actin filaments. In other words, what determines the fate of an actin filament?

In the Jansen lab, we are using a combination of genetics, biomimetic systems, cell imaging, multi-color in vitro TIRF microscopy and single molecule techniques to investigate how two important, but heavily understudied families of actin-binding proteins, the Tropomyosins and the Coronins, play a role as regulatory hubs that generate different actin filament populations that are optimally suited to mediate intracellular trafficking, cell migration, cytokinesis or cell adhesion. For more information on past and current projects, go to https://silviajansen.wixsite.com/jansen-lab.

Required Qualifications

  • Ph.D.
  • Experience in molecular biology, protein expression and purification, live-cell imaging
  • Experience with protein expression in insect cells as well as TEM are a plus

Preferred Qualifications

Demonstrated ability to implement laboratory procedures, conduct research and records findings.

Salary Range

Base pay commensurate with experience.

Benefits

This position is eligible for full-time benefits. Please visit our website at http://hr.wustl.edu to view a summary of benefits.

Applicant Special Instructions

Candidates should email a current CV and contact information for three references to Dr. Silvia Jansen at silvia.jansen@wustl.edu.

EOE Statement

Washington University is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, genetic information, disability, or protected veteran status.

Job Title: Postdoctoral Research Associate - Cell Biology and Physiology - 41978

Job ID: 41978

Location: Medical School

Full/Part Time: Full-Time

Regular/Temporary: Regular