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Washington University of St. Louis Staff Scientist - Developmental Biology - 49990 in St. Louis, Missouri

Job Type/Schedule

This position is full-time and works approximately 40 hours per week.

Department Name/Job Location

This position is in the Department of Developmental Biology. This position is for the Medical School Campus.

Essential Functions

POSITION SUMMARY:

The Imai lab aims to better understand the systemic regulatory mechanisms of aging and longevity in mammals. The position affords the exciting opportunity explore a new and rapidly growing research effort to understand the connection between NAD metabolism and autophagy within the context of metabolism and aging. This proposed research aims to investigate a possible functional link between NAD+ metabolism and autophagy, mainly in the liver and the hypothalamus, under multiple pathophysiological conditions. Applicants with a strong background in the field of autophagy, extensive experience using rodent models, and having strong molecular biology, cell culture, and protein analysis skills are encouraged to apply.

The position assists in developing and conducting research projects, including experimental design, data analysis and documentation of experimental results.

PRIMARY DUTIES AND RESPONSIBILITIES:

  1. Following instructions and discussions with the principal investigator, designs research protocols, including developing procedures for the collection, verification and management of data.
  2. Assists with grant preparation and reporting.
  3. Performs complex statistical analysis of data collected and writes interpretative reports. Verifies the correctness of the data submitted and makes recommendations based on these analyses.
  4. Documents research topics and prepares and submits papers based on research work to publications and committees for publication or presentation to peers.
  5. Solves practical problems relating to difficulties with equipment or test subjects. Suggests technical or procedural improvements in testing methods.
  6. Conducts literature searches related to research project.

Required Qualifications

Master’s degree with four years of experience in research lab operations or an equivalent combination of education and experience equaling nine years.

Preferred Qualifications

  • Ph.D. degree or foreign equivalent in biomedical/cell/molecular biology or related fields.
  • Background or strong interest in the field of autophagy and mouse physiology.
  • Demonstrated success executing projects involving cellular and animal models of disease.
  • Proficiency in molecular biology skills, including protein analyses such as western blotting and immunoprecipitation.
  • Experience handling, performing experiments with, and breeding of tissue-specific KO mice.
  • Cell culture techniques, including use of primary hepatocytes and neurons.
  • Experience with reading and understanding scientific papers and applying these concepts to experimental design.
  • Experience with designing, analyzing, and interpreting experimental data.
  • Computer literacy, including the ability to use a variety of software packages to analyze data.
  • Ability to analyze and interpret statistical data and to communicate data in a clear, concise manner.
  • Demonstrated ability to be highly productive in a fluid, fast-paced and collaborative work environment.
  • Exceptional written and oral communication skills.
  • Outstanding interpersonal and leadership skills.

Salary Range

The hiring range for this position is $46,779 - $63,170 annually.

Pre-Employment Screening

All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. Current employees applying for a new position within the university may be subject to this requirement. The screenings will include a criminal background check and, as applicable for the position, other background checks, drug screen, employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.

Department Summary

The Developmental Biology Department encompasses a group of faculty with primary interests and expertise in developmental biology, stem cell biology, physiology and aging. At present, the principal research activities of this department are focused on the profoundly complex challenge of attaining a mechanistic understanding of organogenesis, encompassing the earliest developmental processes in the embryo, organism and cellular physiology, and tissue homeostasis and repair. The ultimate goal is to understand development and physiology in enough detail to recapitulate organogenesis in vitro and to generate replacement tissues that function_ in vivo_. This long-term goal has immense potential benefit for human health. A comprehensive understanding and integration of developmental biology, stem cell biology, physiology and aging will facilitate translational approaches to preventing and treating a variety of genetic, developmental, metabolic and neurological diseases, and cancer.

Please visit http://devbio.wustl.edu for more information.

Benefits

This position is eligible for full-time benefits. Please click the following link to view a summary of benefits: https://wustl.box.com/s/8wkhs25yssf0775x9d6nd6vqa7obpth7.

Applicant Special Instructions

WORKING CONDITIONS:

This position works in a laboratory environment with potential exposure to biological and chemical hazards. The individual must be physically able to wear protective equipment and to provide standard care to research animals.

EOE Statement

Washington University is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, genetic information, disability, or protected veteran status.

Job Title: Staff Scientist - Developmental Biology - 49990

Job ID: 49990

Location: Medical School

Full/Part Time: Full-Time

Regular/Temporary: Regular

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